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Enzolifesciences/Calcineurin A polyclonal antibody/ADI-SPA-610-D/50µg
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发布时间：2024-05-16
Product Specification:
| Host: | Rabbit |
| Immunogen: | Synthetic peptide corresponding to human calcineurin A. |
| UniProt ID: | P16298 |
| GenBank ID: | M29550 |
| Species reactivity: | Human, Mouse, RatBovine, Chicken, Dog, Drosophila, Hamster, Monkey, Porcine, Rabbit, Sheep |
| Applications: | IP, WB |
| Recommended Dilutions/Conditions: | Western Blot (1:1,000, ECL)Suggested dilutions/conditions may not be available for all applications.Optimal conditions must be determined individually for each application. |
| Application Notes: | Detects a band of ~61kDa by Western blot. |
| Purity Detail: | Protein A affinity purified. |
| Formulation: | Liquid. In PBS containing 50% glycerol and 0.09% sodium azide. |
| Shipping: | Shipped on Blue Ice |
| Long Term Storage: | -20°C |
| Scientific Background: | Calcineurin is a Ca2+/Calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. Calcineurin, which is the target of immunosuppressant drugs such as cyclosporin A and FK506, controls the translocation of Nuclear factors of activated T-cells (NFAT), a family of transcriptional activators that control the expression of cytokine genes essential to immune response, from the cytosol into the nucleus of activated T-cells. |
本文链接： http://lifesci.immuno-online.com/view-1463651796.html
发布于 ： 2024-05-16
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